Streptococcus pneumoniae DNA load in blood as a marker of infection in patients with community-acquired pneumonia.

@article{Peters2009StreptococcusPD,
  title={Streptococcus pneumoniae DNA load in blood as a marker of infection in patients with community-acquired pneumonia.},
  author={Remco P H Peters and Richard F. de Boer and Tim Schuurman and Sonja Gierveld and Mirjam A M D Kooistra-Smid and Michiel A. van Agtmael and Christina M. J. E. Vandenbroucke-Grauls and Maike C J Persoons and Paul H. M. Savelkoul},
  journal={Journal of clinical microbiology},
  year={2009},
  volume={47 10},
  pages={3308-12}
}
Direct detection of Streptococcus pneumoniae DNA in blood adds to culture results in the etiological diagnosis of patients with community-acquired pneumonia (CAP). Quantification of the amount of DNA, the bacterial DNA load (BDL), provides a measurement of DNAemia that may increase the understanding of the clinical relevance of S. pneumoniae DNA in blood. We evaluated the S. pneumoniae BDL as a diagnostic tool in adult patients with CAP. The BDL was determined in whole-blood samples collected… CONTINUE READING