Streptococcus pneumoniae: transmission, colonization and invasion

  title={Streptococcus pneumoniae: transmission, colonization and invasion},
  author={Jeffrey N Weiser and Daniela M Ferreira and James C Paton},
  journal={Nature Reviews Microbiology},
Streptococcus pneumoniae has a complex relationship with its obligate human host. On the one hand, the pneumococci are highly adapted commensals, and their main reservoir on the mucosal surface of the upper airways of carriers enables transmission. On the other hand, they can cause severe disease when bacterial and host factors allow them to invade essentially sterile sites, such as the middle ear spaces, lungs, bloodstream and meninges. Transmission, colonization and invasion depend on the… CONTINUE READING
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