Streptococcal upper respiratory tract infections and psychosocial stress predict future tic and obsessive-compulsive symptom severity in children and adolescents with Tourette syndrome and obsessive-compulsive disorder.

@article{Lin2010StreptococcalUR,
  title={Streptococcal upper respiratory tract infections and psychosocial stress predict future tic and obsessive-compulsive symptom severity in children and adolescents with Tourette syndrome and obsessive-compulsive disorder.},
  author={Haiqun Lin and Kyle A. Williams and Liliya Katsovich and Diane B Findley and Heidi Grantz and Paul J. Lombroso and Robert T. F. A. King and Debra E. Bessen and Dwight Richard Johnson and Edward Lawrence Kaplan and Angeli Landeros-Weisenberger and Heping Zhang and James F. Leckman},
  journal={Biological psychiatry},
  year={2010},
  volume={67 7},
  pages={684-91}
}
BACKGROUND One goal of this prospective longitudinal study was to identify new group A beta-hemolytic streptococcal infections (GABHS) in children and adolescents with Tourette syndrome (TS) and/or obsessive-compulsive disorder (OCD) compared with healthy control subjects. We then examined the power of GABHS infections and measures of psychosocial stress to predict future tic, obsessive-compulsive (OC), and depressive symptom severity. METHODS Consecutive ratings of tic, OC, and depressive… CONTINUE READING