Streptococcal superantigens: categorization and clinical associations.

@article{Commons2014StreptococcalSC,
  title={Streptococcal superantigens: categorization and clinical associations.},
  author={Robert James Commons and Pierre R Smeesters and Thomas Proft and John D Fraser and Roy M Robins-Browne and Nigel Curtis},
  journal={Trends in molecular medicine},
  year={2014},
  volume={20 1},
  pages={
          48-62
        }
}
Superantigens are key virulence factors in the immunopathogenesis of invasive disease caused by group A streptococcus. These protein exotoxins have also been associated with severe group C and group G streptococcal infections. A number of novel streptococcal superantigens have recently been described with some resulting confusion in their classification. In addition to clarifying the nomenclature of streptococcal superantigens and proposing guidelines for their categorization, this review… CONTINUE READING
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