Stratus Not Altocumulus: A New View of the Yeast Protein Interaction Network

@article{Batada2006StratusNA,
  title={Stratus Not Altocumulus: A New View of the Yeast Protein Interaction Network},
  author={Nizar N. Batada and Teresa Reguly and Ashton Breitkreutz and Lorrie Boucher and Bobby-Joe Breitkreutz and Laurence D. Hurst and Michael D Tyers},
  journal={PLoS Biology},
  year={2006},
  volume={4},
  pages={101 - 113}
}
Systems biology approaches can reveal intermediary levels of organization between genotype and phenotype that often underlie biological phenomena such as polygenic effects and protein dispensability. An important conceptualization is the module, which is loosely defined as a cohort of proteins that perform a dedicated cellular task. Based on a computational analysis of limited interaction datasets in the budding yeast Saccharomyces cerevisiae, it has been suggested that the global protein… CONTINUE READING
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