Strategies to overcome extended-spectrum β-lactamases (ESBLs) and AmpC β-lactamases in shigellae.

@article{Livermore2011StrategiesTO,
  title={Strategies to overcome extended-spectrum β-lactamases (ESBLs) and AmpC β-lactamases in shigellae.},
  author={David Martin Livermore and Shazad Mushtaq and Tue Minh-Nhat Nguyen and Marina Warner},
  journal={International journal of antimicrobial agents},
  year={2011},
  volume={37 5},
  pages={
          405-9
        }
}
Oral cephalosporins and mecillinam are used to treat Shigella infections, but are compromised by extended-spectrum β-lactamases (ESBLs) and plasmid AmpC β-lactamases. Potential solutions include combining an oral or intravenous cephalosporin with a β-lactamase inhibitor (BLI) or using an oral penem. These strategies were examined using Escherichia coli transconjugants and clinical isolates with ESBLs or AmpC, as a proxy for shigellae. The Clinical and Laboratory Standards Institute agar… CONTINUE READING
Highly Cited
This paper has 27 citations. REVIEW CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 11 extracted citations