Strategies to manage antifungal drug resistance.

  title={Strategies to manage antifungal drug resistance.},
  author={H. K. Tseng and John R Perfect},
  journal={Expert opinion on pharmacotherapy},
  volume={12 2},
INTRODUCTION Invasive fungal infections continue to cause significant morbidity and mortality in immunocompromised hosts. From more than half a million deaths from cryptococcosis in sub-Saharan Africa to an unchanging death rate from invasive candidiasis, despite three antifungal classes of drugs, insights into better strategies to reduce therapeutic failures or resistance are needed. AREAS COVERED This review examines the issues around antifungal drug resistance from both a basic description… CONTINUE READING