Strategies to inhibit entry of HBV and HDV into hepatocytes.

@article{Urban2014StrategiesTI,
  title={Strategies to inhibit entry of HBV and HDV into hepatocytes.},
  author={Stephan Urban and Ralf Bartenschlager and Ralf Kubitz and Fabien Zoulim},
  journal={Gastroenterology},
  year={2014},
  volume={147 1},
  pages={48-64}
}
Although there has been much research into the pathogenesis and treatment of hepatitis B virus (HBV) and hepatitis D virus (HDV) infections, we still do not completely understand how these pathogens enter hepatocytes. This is because in vitro infection studies have only been performed in primary human hepatocytes. Development of a polarizable, HBV-susceptible human hepatoma cell line and studies of primary hepatocytes from Tupaia belangeri have provided important insights into the viral and… CONTINUE READING
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