Strategies to improve compliance with narcotic antagonists.

  title={Strategies to improve compliance with narcotic antagonists.},
  author={Thomas R. Kosten and Herbert D. Kleber},
  journal={The American journal of drug and alcohol abuse},
  volume={10 2},
The pharmacologic promise of naltrexone has not been matched by therapeutic usefulness. Plagued by difficulties in the induction period and very high dropout, the drug remains limited to a very small segment of the opiate-addited population. Some programs have managed, however, to substantially improve on these problems and such strategies will be discussed. The paper will look at the different problems raised during the high dropout periods of induction, the first month of stabilization, and… CONTINUE READING

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