Strategies of Tumor Immune Evasion

@article{Seliger2012StrategiesOT,
  title={Strategies of Tumor Immune Evasion},
  author={Barbara Seliger},
  journal={BioDrugs},
  year={2012},
  volume={19},
  pages={347-354}
}
During the last decade, increased understanding of the molecular mechanisms responsible for immune activation to protect against challenges by tumor cells has revolutionized the field of immunotherapy research. It has been demonstrated that the dysfunction of the host’s immune system represents one of the major mechanisms by which tumors evade immunosurveillance. This is due, for example, to T cell anergy, the existence of regulatory T cells, and systemic defects of dendritic cells derived from… 
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