Strategies for the Bioequivalence Assessment of Topical Dermatological Dosage Forms

@article{Kanfer2010StrategiesFT,
  title={Strategies for the Bioequivalence Assessment of Topical Dermatological Dosage Forms},
  author={Isadore Kanfer},
  journal={Journal of Bioequivalence \& Bioavailability},
  year={2010},
  volume={2},
  pages={102-110}
}
  • I. Kanfer
  • Published 30 September 2010
  • Medicine
  • Journal of Bioequivalence & Bioavailability
The assessment of the bioequivalence of topical products not intended for absorption into the systemic circulation has presented a formidable challenge over the years. In particular, dermatological dosage forms such as creams, ointments, lotions and gels, apart from those containing topical corticosteroids, cannot readily be assessed for bioequivalence using “conventional” methodology and the only recourse to-date has been to undertake tedious, time consuming and expensive clinical end-point… 
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