Strategies for targeting primate neural circuits with viral vectors.

  title={Strategies for targeting primate neural circuits with viral vectors.},
  author={Yasmine El-Shamayleh and A M Ni and Gregory D. Horwitz},
  journal={Journal of neurophysiology},
  volume={116 1},
Understanding how the brain works requires understanding how different types of neurons contribute to circuit function and organism behavior. Progress on this front has been accelerated by optogenetics and chemogenetics, which provide an unprecedented level of control over distinct neuronal types in small animals. In primates, however, targeting specific types of neurons with these tools remains challenging. In this review, we discuss existing and emerging strategies for directing genetic… CONTINUE READING


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