• Corpus ID: 20764003

Strategies for protein structure model generation

@article{Abeln2017StrategiesFP,
  title={Strategies for protein structure model generation},
  author={Sanne Abeln and Jaap Heringa and K. Anton Feenstra},
  journal={arXiv: Biomolecules},
  year={2017}
}
This chapter deals with approaches for protein three-dimensional structure prediction, starting out from a single input sequence with unknown struc- ture, the 'query' or 'target' sequence. Both template based and template free modelling techniques are treated, and how resulting structural models may be selected and refined. We give a concrete flowchart for how to de- cide which modelling strategy is best suited in particular circumstances, and which steps need to be taken in each strategy… 

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