Strategies for prophylaxis against prosthetic valve endocarditis: a review article.

Prosthetic valve endocarditis (PVE) is an important cause of the morbidity and mortality associated with heart valve replacement surgery. Once established, it carries a mortality rate that may be as high as 70%. The only treatment for established PVE is rigorous intravenous antimicrobial therapy, although this has extremely limited success. The majority of… CONTINUE READING