Strategies for Homology-Based ncRNA Gene Annotation

  • Axel Mosiga, Liang Zhua, Peter F. Stadlerd
  • Published 2009

Abstract

Most non-coding RNAs are short and/or poorly conserved in sequence. Most of the longer examples, furthermore, consist of a collection of conserved structural motifs rather that a coherent globally conserved secondary structure. As a consequence, the conceptually simple problem of homology search becomes a complex and technically demanding task. Despite the… (More)

Topics

5 Figures and Tables

Slides referencing similar topics