Strategies and processes to decellularize and recellularize hearts to generate functional organs and reduce the risk of thrombosis.

Abstract

Heart failure is one of the leading causes of death in the United States. Current therapies, such as heart transplants and bioartificial hearts, are helpful, but not optimal. Decellularization of porcine whole hearts followed by recellularization with patient-specific human cells may provide the ultimate solution for patients with heart failure. Great… (More)
DOI: 10.1089/ten.TEB.2014.0192

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