Strain variation in response to lung ischemia: role of MMP-12

@inproceedings{Tankersley2012StrainVI,
  title={Strain variation in response to lung ischemia: role of MMP-12},
  author={Clarke G. Tankersley and Aigul Moldobaeva and Elizabeth M Wagner},
  booktitle={Respiratory research},
  year={2012}
}
BackgroundSystemic neovascularization of the lung during chronic ischemia has been observed in all mammals studied. However, the proteins that orchestrate the complex interaction of new vessel growth and tunneling through lung tissue matrix have not been described. Although previous work has demonstrated the CXC chemokines are essential growth factors in the process of angiogenesis in mice and rats, key matrix proteins have not been identified.MethodsSince the degradation of chemokines has been… CONTINUE READING
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