• Biology, Medicine
  • Published in
    Journal of clinical…
    1999

Strain variation in adenovirus serotypes 4 and 7a causing acute respiratory disease.

@article{CrawfordMiksza1999StrainVI,
  title={Strain variation in adenovirus serotypes 4 and 7a causing acute respiratory disease.},
  author={Leta Crawford-Miksza and R N Nang and David P. Schnurr},
  journal={Journal of clinical microbiology},
  year={1999},
  volume={37 4},
  pages={
          1107-12
        }
}
In order to determine the suitability of vaccine strains established in the 1960s for a new vaccine, a comprehensive study of strain variation of adenovirus serotype 4 (AV 4) and AV 7 was undertaken. A 1,500-bp region of the hexon gene containing the AV neutralization epitopes from prototype, vaccine, and community-acquired strains and from wild-type strains from military personnel that cause acute respiratory disease (ARD) was sequenced and analyzed. The whole hexon gene from prototype strains… CONTINUE READING

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Molecular analysis of adenovirus isolates from vaccinated and unvaccinated young adults.

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