Strain specificity of spontaneous and adrenergically induced HSV-1 ocular reactivation in latently infected rabbits.

@article{Hill1987StrainSO,
  title={Strain specificity of spontaneous and adrenergically induced HSV-1 ocular reactivation in latently infected rabbits.},
  author={James A. Hill and Mark A. Rayfield and Yuro Haruta},
  journal={Current eye research},
  year={1987},
  volume={6 1},
  pages={91-7}
}
Spontaneous ocular shedding and adrenergic induction of ocular shedding were examined in rabbits infected with ten strains of herpes simplex virus type 1 (HSV-1): McKrae, KOS, F, Rodanus, 17 Syn+, RE, E-43, SC-16, MacIntyre, and CGA-3. All ocular inoculations were with 50 microliter of HSV-1 with titers between 1-10 X 10(6) PFU/ml. All corneas, except those that received the McKrae strain, were scarified. Acute ocular infection was determined by slit-lamp biomicroscopy. Dendritic keratitis or… CONTINUE READING