Strain distribution pattern of susceptibility to immune-mediated nephritis.

Abstract

The genetic basis of immune-mediated nephritis is poorly understood. Recent studies have demonstrated that the NZW mouse strain is more prone to immune-mediated nephritis compared with C57BL/6 and BALB/c strains. The present study extends these findings by challenging 12 additional inbred strains of mice with rabbit anti-mouse glomerular basement membrane… (More)

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@article{Xie2004StrainDP, title={Strain distribution pattern of susceptibility to immune-mediated nephritis.}, author={Chun Xie and Ruchi K. Sharma and Hong-Wei Wang and Xin Zhou and Chandra Mohan}, journal={Journal of immunology}, year={2004}, volume={172 8}, pages={5047-55} }