Strain difference of DNA-binding activity of NF-kappaB and cytokine gene expression in spleen dendritic cells of Lewis and Fischer rats.

To investigate the mechanisms of different responses to inflammatory stimuli between Lewis and Fischer rats, the DNA-binding activity of the nuclear factor kappa B (NF-kappaB) and cytokine production of spleen dendritic cells (SDC) in Lewis and Fischer rats after peptidoglycan-polysaccharide (PG-PS) treatment were determined. The results show that the DNA… CONTINUE READING