Strain-dependent performance in nicotine-induced conditioned place preference.

  title={Strain-dependent performance in nicotine-induced conditioned place preference.},
  author={Munir Gunes Kutlu and Leonardo A. Ortega and Thomas J Gould},
  journal={Behavioral neuroscience},
  volume={129 1},
Nicotine addiction is most likely a result of a combination of factors including the rewarding effects of the drug; these effects, however, might be influenced by genetic background. Using a conditioned place preference (CPP) paradigm and 8 inbred mouse strains, we conducted an initial examination of the role of genetic background in the rewarding effects of nicotine. Following habituation and initial place preference test, inbred strains (A/J, BALB/cByJ, C3H/HeJ, C57BL/6J, CBA/J, DBA/1J, DBA… CONTINUE READING

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