Strain-Specific Regulation of Striatal Phenotype in Drd2-eGFP BAC Transgenic Mice

@article{Chan2012StrainSpecificRO,
  title={Strain-Specific Regulation of Striatal Phenotype in Drd2-eGFP BAC Transgenic Mice},
  author={C. S. Chan and J. Peterson and Tracy S Gertler and Kelly E. Glajch and Ruth Quintana and Qiaoling Cui and Luke E. Sebel and Joshua L. Plotkin and W. Shen and M. Heiman and N. Heintz and P. Greengard and D. Surmeier},
  journal={The Journal of Neuroscience},
  year={2012},
  volume={32},
  pages={9124 - 9132}
}
Mice carrying bacterial artificial chromosome (BAC) transgenes have become important tools for neuroscientists, providing a powerful means of dissecting complex neural circuits in the brain. Recently, it was reported that one popular line of these mice—mice possessing a BAC transgene with a D2 dopamine receptor (Drd2) promoter construct coupled to an enhanced green fluorescent protein (eGFP) reporter—had abnormal striatal gene expression, physiology, and motor behavior. Unlike most of the work… Expand
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