Strain-Dependent Consequences of Zika Virus Infection and Differential Impact on Neural Development

@inproceedings{Goodfellow2018StrainDependentCO,
  title={Strain-Dependent Consequences of Zika Virus Infection and Differential Impact on Neural Development},
  author={Forrest Goodfellow and Katherine A Willard and Xian Wei Wu and Shelley L. Scoville and Steven L Stice and Melinda A Brindley},
  booktitle={Viruses},
  year={2018}
}
Maternal infection with Zika virus (ZIKV) during pregnancy can result in neonatal abnormalities, including neurological dysfunction and microcephaly. Experimental models of congenital Zika syndrome identified neural progenitor cells as a target of viral infection. Neural progenitor cells are responsible for populating the developing central nervous system with neurons and glia. Neural progenitor dysfunction can lead to severe birth defects, namely, lissencephaly, microcephaly, and cognitive… CONTINUE READING
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