Straight and curved conformations of FtsZ are regulated by GTP hydrolysis.

  title={Straight and curved conformations of FtsZ are regulated by GTP hydrolysis.},
  author={Chunlin Lu and Mary Reedy and Harold P Erickson},
  journal={Journal of bacteriology},
  volume={182 1},
FtsZ assembles in vitro into protofilaments that can adopt two conformations-the straight conformation, which can assemble further into two-dimensional protofilament sheets, and the curved conformation, which forms minirings about 23 nm in diameter. Here, we describe the structure of FtsZ tubes, which are a variation of the curved conformation. In the tube the curved protofilament forms a shallow helix with a diameter of 23 nm and a pitch of 18 or 24 degrees. We suggest that this shallow helix… CONTINUE READING
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