Store depletion and calcium influx.

  title={Store depletion and calcium influx.},
  author={A. Parekh and R. Penner},
  journal={Physiological reviews},
  volume={77 4},
  • A. Parekh, R. Penner
  • Published 1997
  • Biology, Medicine
  • Physiological reviews
  • Calcium influx in nonexcitable cells regulates such diverse processes as exocytosis, contraction, enzyme control, gene regulation, cell proliferation, and apoptosis. The dominant Ca2+ entry pathway in these cells is the store-operated one, in which Ca2+ entry is governed by the Ca2+ content of the agonist-sensitive intracellular Ca2+ stores. Only recently has a Ca2+ current been described that is activated by store depletion. The properties of this new current, called Ca2+ release-activated Ca2… CONTINUE READING
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