Store‐operated interactions between plasmalemmal STIM1 and TRPC1 proteins stimulate PLCβ1 to induce TRPC1 channel activation in vascular smooth muscle cells

Abstract

KEY POINTS Depletion of Ca2+ stores activates store-operated channels (SOCs), which mediate Ca2+ entry pathways that regulate cellular processes such as contraction, proliferation and gene expression. In vascular smooth muscle cells (VSMCs), stimulation of SOCs composed of canonical transient receptor potential channel 1 (TRPC1) proteins requires G protein… (More)
DOI: 10.1113/JP273302

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@inproceedings{Shi2017StoreoperatedIB, title={Store‐operated interactions between plasmalemmal STIM1 and TRPC1 proteins stimulate PLCβ1 to induce TRPC1 channel activation in vascular smooth muscle cells}, author={Jian Shi and Francesc Miralles and Lutz Birnbaumer and William A. Large and Anthony P Albert}, booktitle={The Journal of physiology}, year={2017} }