Storage iron kinetics. VII. A biologic model for reticuloendothelial iron transport.

@article{Fillet1974StorageIK,
  title={Storage iron kinetics. VII. A biologic model for reticuloendothelial iron transport.},
  author={Georges Fillet and James D. Cook and Clement A. Finch},
  journal={The Journal of clinical investigation},
  year={1974},
  volume={53 6},
  pages={1527-33}
}
The processing of erythrocyte iron by the reticuloendothelial cell has been characterized by kinetic measurements of blood radioactivity made after the intravenous injection of heat-damaged erythrocytes labeled with (59)Fe and of transferrin-bound (55)Fe. The early reticuloendothelial release of iron, a matter of hours, was calculated from the plasma turnover rate of (55)Fe and the plasma reappearance of (59)Fe. Late release was calculated from the ratio of the cumulative incorporation of both… CONTINUE READING

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