Stop-signal inhibition disrupted by damage to right inferior frontal gyrus in humans

  title={Stop-signal inhibition disrupted by damage to right inferior frontal gyrus in humans},
  author={A. Aron and P. Fletcher and E. Bullmore and B. Sahakian and T. Robbins},
  journal={Nature Neuroscience},
  • A. Aron, P. Fletcher, +2 authors T. Robbins
  • Published 2003
  • Psychology, Medicine
  • Nature Neuroscience
  • The precise localization of executive functions such as response inhibition within the prefrontal cortex (PFC), although theoretically crucial, has proven to be controversial and difficult. Functional neuroimaging has contributed importantly to this debate, but as human cortical lesions are seldom discrete, the literature still lacks definitive neuropsychological evidence that a specific region is necessary for task performance. We overcame this limitation by using a new observer-independent… CONTINUE READING
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