Stomach cancer in transgenic mice expressing human papillomavirus type 16 early region genes from a keratin promoter.

Abstract

Certain human papillomaviruses (HPVs) have been implicated as important contributory factors in the development of cervical carcinoma and other epithelial malignancies. In order to investigate the role of papillomavirus early gene expression in epithelial oncogenesis in vivo, we produced transgenic mice expressing HPV-16 early region genes from the promoter… (More)

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@article{Searle1994StomachCI, title={Stomach cancer in transgenic mice expressing human papillomavirus type 16 early region genes from a keratin promoter.}, author={Peter F. Searle and D. Paul Thomas and Kimberly Faulkner and Jon M. Tinsley}, journal={The Journal of general virology}, year={1994}, volume={75 ( Pt 5)}, pages={1125-37} }