Stoichiometric model and metabolic flux analysis for Leptospirillum ferrooxidans.

  title={Stoichiometric model and metabolic flux analysis for Leptospirillum ferrooxidans.},
  author={Margret Merino and Barbara A. Andrews and Juan A. Asenjo},
  journal={Biotechnology and bioengineering},
  volume={107 4},
A metabolic model for Leptospirillum ferrooxidans was developed based on the genomic information of an analogous iron oxidizing bacteria and on the pathways of ferrous iron oxidation, nitrogen and CO(2) assimilation based on experimental evidence for L. ferrooxidans found in the literature. From this metabolic reconstruction, a stoichiometric model was built, which includes 86 reactions describing the main catabolic and anabolic aspects of its metabolism. The model obtained has 2 degrees of… CONTINUE READING

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