Stochastic nonlinear dynamics of confined cell migration in two-state systems

@article{Brckner2019StochasticND,
  title={Stochastic nonlinear dynamics of confined cell migration in two-state systems},
  author={David B. Br{\"u}ckner and Alexandra Fink and Christoph Schreiber and Peter Johan Friedrich R{\"o}ttgermann and Joachim O. R{\"a}dler and Chase P. Broedersz},
  journal={Nature Physics},
  year={2019},
  volume={15},
  pages={595-601}
}
Migrating cells in physiological processes, including development, homeostasis and cancer, encounter structured environments and are forced to overcome physical obstacles. Yet, the dynamics of confined cell migration remains poorly understood, and thus there is a need to study the complex motility of cells in controlled confining microenvironments. Here, we develop two-state micropatterns, consisting of two adhesive sites connected by a thin constriction, in which migrating cells perform… Expand
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