Stochastic model of T Cell repolarization during target elimination (II)

@article{Hork2021StochasticMO,
  title={Stochastic model of T Cell repolarization during target elimination (II)},
  author={Ivan Horň{\'a}k and Heiko Rieger},
  journal={bioRxiv},
  year={2021}
}
Cytotoxic T lymphocytes (T cells) and natural killer cells form a tight contact, the immunological synapse (IS), with target cells, where they release their lytic granules containing perforin/granzyme and cytokine containing vesicles. During this process the cell repolarizes and moves the microtubule organizing center (MTOC) towards the IS. In the first part of our work we developed a computational model for the molecular-motor-driven motion of the MT cytoskeleton during T cell polarization and… 

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