Stochastic branching-diffusion models for gene expression.

Abstract

A challenge to both understanding and modeling biochemical networks is integrating the effects of diffusion and stochasticity. Here, we use the theory of branching processes to give exact analytical expressions for the mean and variance of protein numbers as a function of time and position in a spatial version of an established model of gene expression. We… (More)
DOI: 10.1073/pnas.1201103109

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