Stochastic Simulation of the Chemoton

  title={Stochastic Simulation of the Chemoton},
  author={Sven Van Segbroeck and Ann Now{\'e} and T. Lenaerts},
  journal={Artificial Life},
Gnti's chemoton model is an illustrious example of a minimal cell model. It is composed of three stoichiometrically coupled autocatalytic subsystems: a metabolism, a template replication process, and a membrane enclosing the other two. Earlier studies on chemoton dynamics yield inconsistent results. Furthermore, they all appealed to deterministic simulations, which do not take into account the stochastic effects induced by small population sizes. We present, for the first time, results of a… 

Two Different Template Replicators Coexisting in the Same Protocell: Stochastic Simulation of an Extended Chemoton Model

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Toward the engineering of minimal living cells

  • P. Luisi
  • Biology
    The Anatomical record
  • 2002
The article focuses on the notion of a synthetic or semi‐synthetic minimal cell, defined as a system that has the minimal and sufficient structural conditions for cellular life, and the outlook of increasing the complexity of these liposome systems so as to arrive at first semi‐Synthetic cells.


  • T. Gánti
  • Engineering
    Cell biology international
  • 2002
The potential difference of energy is the driving power behind every continuously functioning engine, machine or device and, in the latter, the pathways of the energy are not manipulated by mechanical or electrical means but by chemical means.

Synthesizing life : Paths to unforeseeable science & technology

Advances in directed evolution and membrane biophysics make the synthesis of simple living cells, if not yet foreseeable reality, an imaginable goal. Overcoming the many scientific challenges along