Stitching together Multiple Data Dimensions Reveals Interacting Metabolomic and Transcriptomic Networks That Modulate Cell Regulation

@inproceedings{Zhu2012StitchingTM,
  title={Stitching together Multiple Data Dimensions Reveals Interacting Metabolomic and Transcriptomic Networks That Modulate Cell Regulation},
  author={Jun Zhu and Pavel Sova and Qiuwei Xu and Kenneth M. Dombek and Ethan Yixun Xu and Heather Vu and Zhidong Tu and Rachel B. Brem and Roger Eugene Bumgarner and Eric E. Schadt},
  booktitle={PLoS biology},
  year={2012}
}
Cells employ multiple levels of regulation, including transcriptional and translational regulation, that drive core biological processes and enable cells to respond to genetic and environmental changes. Small-molecule metabolites are one category of critical cellular intermediates that can influence as well as be a target of cellular regulations. Because metabolites represent the direct output of protein-mediated cellular processes, endogenous metabolite concentrations can closely reflect… CONTINUE READING

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The landscape of genetic complexity across 5,700 gene expression traits in yeast.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 2005
VIEW 6 EXCERPTS
HIGHLY INFLUENTIAL

Estimating the dimension of a model

VIEW 3 EXCERPTS
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