Stimulus-specific enhancement of fear extinction during slow-wave sleep

  title={Stimulus-specific enhancement of fear extinction during slow-wave sleep},
  author={Katherina K Y Hauner and James D. Howard and Christina Zelano and Jay A. Gottfried},
  booktitle={Nature Neuroscience},
Sleep can strengthen memory for emotional information, but whether emotional memories can be specifically targeted and modified during sleep is unknown. In human subjects who underwent olfactory contextual fear conditioning, re-exposure to the odorant context in slow-wave sleep promoted stimulus-specific fear extinction, with parallel reductions of hippocampal activity and reorganization of amygdala ensemble patterns. Thus, fear extinction may be selectively enhanced during sleep, even without… CONTINUE READING
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