Stimulus-evoked high frequency oscillations are present in neuronal networks on microelectrode arrays

@inproceedings{Hales2012StimulusevokedHF,
  title={Stimulus-evoked high frequency oscillations are present in neuronal networks on microelectrode arrays},
  author={Chadwick M. Hales and Riley Zeller-Townson and Jonathan P Newman and James T. Shoemaker and Nathan J. Killian and Steve M. Potter},
  booktitle={Front. Neural Circuits},
  year={2012}
}
Pathological high frequency oscillations (250-600 Hz) are present in the brains of epileptic animals and humans. The etiology of these oscillations and how they contribute to the diseased state remains unclear. This work identifies the presence of microstimulation-evoked high frequency oscillations (250-400 Hz) in dissociated neuronal networks cultured on microelectrode arrays (MEAs). Oscillations are more apparent with higher stimulus voltages. As with in vivo studies, activity is isolated to… CONTINUE READING
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