Stimulus dependence of two-state fluctuations of membrane potential in cat visual cortex

@article{Anderson2000StimulusDO,
  title={Stimulus dependence of two-state fluctuations of membrane potential in cat visual cortex},
  author={Jeffrey S. Anderson and I. Lampl and I. Reichova and M. Carandini and D. Ferster},
  journal={Nature Neuroscience},
  year={2000},
  volume={3},
  pages={617-621}
}
Membrane potentials of cortical neurons fluctuate between a hyperpolarized (‘down’) state and a depolarized (‘up’) state which may be separated by up to 30 mV, reflecting rapid but infrequent transitions between two patterns of synaptic input. Here we show that such fluctuations may contribute to representation of visual stimuli by cortical cells. In complex cells of anesthetized cats, where such fluctuations are most prominent, prolonged visual stimulation increased the probability of the up… Expand
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