Stimulatory effect of polyprenoic acid E5166 on 2-deoxy-D-glucose uptake by Swiss 3T3 cells.

3,7,11,15-Tetramethyl-2,4,6,10,14-hexadecapentaenoic acid (E5166), a synthetic analog of retinoic acid, increased 2-deoxy-D-glucose (2DG) uptake in a dose and time-dependent manner in mouse fibroblasts, Swiss 3T3 cells. Kinetic analysis of 2DG uptake showed that the Vmax for 2DG uptake by E5166-treated cells was greater than that of the control, while the… (More)