Stimulatory effect of dexamethasone on angiotensin-converting enzyme in neonatal rat cardiac myocytes.

@article{BarretoChaves2000StimulatoryEO,
  title={Stimulatory effect of dexamethasone on angiotensin-converting enzyme in neonatal rat cardiac myocytes.},
  author={Maria Luiza Morais Barreto-Chaves and Axel Heimann and Jos{\'e} Eduardo Krieger},
  journal={Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas},
  year={2000},
  volume={33 6},
  pages={661-4}
}
Angiotensin-converting enzyme (ACE) plays a central role in cardiac remodeling associated with pathological conditions such as myocardial infarction. The existence of different cell types in the heart expressing components of the renin-angiotensin system makes it difficult to evaluate their relative role under physiological and pathological conditions. Since myocytes are the predominant cellular constituent of the heart by mass, in the present study we studied the effects of glucocorticoids on… CONTINUE READING