Stimulatory effect of antidepressants on the production of IL-6.

  title={Stimulatory effect of antidepressants on the production of IL-6.},
  author={Marta Kubera and Gunter R L Kenis and Eug{\`e}ne Bosmans and Małgorzata Kajta and Agnieszka Basta-Kaim and Simon S Scharp{\'e} and Bogusława Budziszewska and Michael Maes},
  journal={International immunopharmacology},
  volume={4 2},
A body of evidence indicates that the therapeutic activity of antidepressants is connected with their modulatory effect on the inflammatory response system and cell-mediated immunity. The present study was carried out to examine the effects of antidepressant agents, such as imipramne, venlafaxine, l-5-hydroxytryptophan, fluoxetine and a combination of l-5-hydroxytryptophan and fluoxetine, on the production of the pleotrophic cytokines TNF-alpha and IL-6. Diluted whole blood from fluoxetine… CONTINUE READING