Stimulatory and inhibitory regulators of the hypothalamo-pituitary-adrenocortical axis.

  • David S. Jessop
  • Published 1999 in
    Bailliere's best practice & research. Clinical…
Short- and long-term metabolic effects of stress are mediated through the hypothalamo-pituitary-adrenocortical (HPA) axis and the sympathetic nervous system. While efficient functioning of these systems is essential for life processes, dysfunction can lead to hypercortisolaemia and inappropriately elevated catecholamines, resulting in immunosuppression and… CONTINUE READING