Stimulatory action of cyclooxygenase inhibitors on hematopoiesis: a review.

  title={Stimulatory action of cyclooxygenase inhibitors on hematopoiesis: a review.},
  author={Michal Hofer and Milan Posp{\'i}{\vs}il and Zuzana Hoferov{\'a} and Lenka Weiterov{\'a} and Denisa Komůrkov{\'a}},
  volume={17 5},
The presented review summarizes experimental data obtained with a mouse model when investigating the relationship between inhibition of prostaglandin production and hematopoiesis. While prostaglandin E2 acts in a negative feedback control of myelopoiesis, inhibition of cyclooxygenases, responsible for its production, shifts the feedback to positive control. Based on these relationships, agents inhibiting cyclo-oxygenases, known as non-steroidal anti-inflammatory drugs (NSAIDs), can activate… CONTINUE READING


Publications referenced by this paper.
Showing 1-10 of 84 references

Similar Papers

Loading similar papers…