Stimulatory action of cyclooxygenase inhibitors on hematopoiesis: a review.

@article{Hofer2012StimulatoryAO,
  title={Stimulatory action of cyclooxygenase inhibitors on hematopoiesis: a review.},
  author={Michal Hofer and Milan Posp{\'i}{\vs}il and Zuzana Hoferov{\'a} and Lenka Weiterov{\'a} and Denisa Komůrkov{\'a}},
  journal={Molecules},
  year={2012},
  volume={17 5},
  pages={5615-25}
}
The presented review summarizes experimental data obtained with a mouse model when investigating the relationship between inhibition of prostaglandin production and hematopoiesis. While prostaglandin E2 acts in a negative feedback control of myelopoiesis, inhibition of cyclooxygenases, responsible for its production, shifts the feedback to positive control. Based on these relationships, agents inhibiting cyclo-oxygenases, known as non-steroidal anti-inflammatory drugs (NSAIDs), can activate… CONTINUE READING

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