Stimulative effects of cortisol and testosterone on bile calcium excretion in thyroparathyroidectomized rats.

  title={Stimulative effects of cortisol and testosterone on bile calcium excretion in thyroparathyroidectomized rats.},
  author={Masayoshi Yamaguchi and Yoshihiko Akiyama and Shoji Okada},
  journal={Journal of pharmacobio-dynamics},
  volume={5 5},
The effects of cortisol and testosterone on calcium metabolism in the hepatic bile system were investigated in thyroparathyroidectomized rats. A single subcutaneous administration of cortisol (0.1 mg/100 g) or testosterone (0.1 mg/100 g) caused a significant fall in serum calcium and a corresponding increase in liver calcium. On the other hand, the excretion of calcium into the bile after a single intraperitoneal injection of calcium chloride (4.0 mg Ca/100 g) was markedly increased by the… 
1 Citations

Women, Stress, and Participation in Possession Cults: A Reexamination of the Calcium Deficiency Hypothesis

Kehoe and Giletti (1981) have argued that the preponderance of women as patients in curing ceremonies is best explained by a variety of dietary inadequacies, particularly by a deficiency of calcium,



Effect of thyrocalcitonin on calcium concentration in liver of intact and thyroparathyroidectomized rats.

The results suggest that the action of TCT on liver calcium does not involve cyclic AMP and is not enhanced by prior administration of theophylline which caused a significant elevation of serum calcium.

Effects of 1,25-dihydroxycholecalciferol on intestinal calcium transport in cortisone-treated rats.

The results support the concept that under the conditions of these experiments in the rat the apparent antagonism between glucocorticoids and vitamin D may be due to steroid hormone-related alterations in end organ function that are independent of any direct interaction between the hormone and the vitamin and that cannot be reversed by the vitamin.

Androgens and enhancement of hypocalcemic response to thyrocalcitonin in rats.

Endogenous androgens and exogenous testoster-one propionate caused inconsistent alterations in the basal levels of serum calcium and phosphate and the sensitization of animals to thyrocalcitonin could not be accounted for by their effects on serum phosphate concentration.

Inhibition by steroids of parathyroid hormone-induced Ca45 release from embryonic rat bone in vitro.

  • P. Stern
  • Biology, Medicine
    The Journal of pharmacology and experimental therapeutics
  • 1969
The results indicate that, at concentrations achieved in vitro, glucocorticoids can inhibit bone resorption by a direct effect on bone and suggest that the in vitro inhibition of bone Resorption produced by steroid hormones at high concentrations is a nonspecific effect.

Transfer of Ca45 across intestinal wall in vitro in relation to action of vitamin D and cortisol.

It is suggested that vitamin D and cortisol influence calcium transport by action on the permeability of cell surfaces to calcium.

Addison's disease in a boy with hypoparathyroidism.

The patient reported here was a 10-year-old boy in whom Addison's disease developed after H1N1 infection, and the clinical impression of hypoparathyroidism and Addison’s disease was verified.

Maximum Biliary Excretion of Bilirubin and Sulfobromophthalein During Anesthesia-Induced Alteration of Rectal Temperature.∗

  • R. RobertsC. KlaassenG. Plaa
  • Biology, Medicine
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine
  • 1967
Experimental techniques commonly employed in maximum biliary excretion studies were shown to significantly alter normal thermoregulatory mechanisms and a decrease in body temperature significantly decreased the bilirubin transport maximum in both rats and mice.