Stimulation of voluntary ethanol intake by cannabinoid receptor agonists in ethanol-preferring sP rats

@article{Colombo2002StimulationOV,
  title={Stimulation of voluntary ethanol intake by cannabinoid receptor agonists in ethanol-preferring sP rats},
  author={Giancarlo Colombo and Salvatore Serra and Giuliana Brunetti and Raquel G{\'o}mez and Samuele Melis and Giovanni Vacca and Mauro A. M. Carai and Gian Luigi Gessa},
  journal={Psychopharmacology},
  year={2002},
  volume={159},
  pages={181-187}
}
Rationale: Recent studies have shown that the cannabinoid CB1 receptor antagonist, SR 141716, is capable of reducing voluntary ethanol intake in rodents, suggesting the involvement of the CB1 receptor in the neural circuitry mediating the positive reinforcing properties of ethanol. Objectives: The present study extended to the agonists the investigation on the pharmacological manipulation of ethanol intake by cannabinoid agents. Methods: Selectively bred, Sardinian alcohol-preferring (sP) rats… CONTINUE READING

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