Stimulation of the locus coeruleus elicits noradrenaline and dopamine release in the medial prefrontal and parietal cortex.

@article{Devoto2005StimulationOT,
  title={Stimulation of the locus coeruleus elicits noradrenaline and dopamine release in the medial prefrontal and parietal cortex.},
  author={Paola Devoto and Giovanna Flore and Pierluigi Saba and Mauro F{\`a} and Gian Luigi Gessa},
  journal={Journal of neurochemistry},
  year={2005},
  volume={92 2},
  pages={368-74}
}
Our previous studies have suggested that dopamine and noradrenaline may be coreleased from noradrenergic nerve terminals in the cerebral cortex. To further clarify this issue, the effect of electrical stimulation of the locus coeruleus on extracellular noradrenaline, dopamine and DOPAC in the medial prefrontal cortex, parietal cortex and caudate nucleus was analysed by microdialysis in freely moving rats. Stimulation of the locus coeruleus for 20 min with evenly spaced pulses at 1 Hz failed to… CONTINUE READING

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