Stimulation of the globus pallidus internus for childhood-onset dystonia.

  title={Stimulation of the globus pallidus internus for childhood-onset dystonia.},
  author={Giovanna Simonetta Zorzi and Carlo Efisio Marras and Nardo Nardocci and Angelo Franzini and Luisa Chiapparini and Elio Maccagnano and Lucia Angelini and Dario Caldiroli and Giovanni Broggi},
  journal={Movement disorders : official journal of the Movement Disorder Society},
  volume={20 9},
We report the results of deep brain stimulation (DBS) of the globus pallidus internus (GPi) in 12 patients with childhood-onset generalized dystonia refractory to medication, including 3 patients with status dystonicus. There were 8 patients who had DYT1-negative primary dystonia, 1 had DYT1-positive dystonia, and 3 had symptomatic dystonia. Stimulation was effective in all but 1 patient. Dystonic postures and movements of the axis and limbs responded to DBS to a greater extent than… CONTINUE READING

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