Stimulation of subthalamic fibre tracts reduces dyskinesias in STN-DBS.

  title={Stimulation of subthalamic fibre tracts reduces dyskinesias in STN-DBS.},
  author={Jan Herzog and Marcus O. Pinsker and M. Wasner and Frank Steigerwald and Stefanie Wailke and Gunther Deuschl and Jens Volkmann},
  journal={Movement disorders : official journal of the Movement Disorder Society},
  volume={22 5},
Rarely, the postoperative management of patients with subthalamic deep brain stimulation (STN-DBS) is complicated by pharmacologically intractable dyskinesias. Here we report that in three of these patients additional stimulation of a proximal contact located within the subthalamic white matter may lead to a significant reduction of dyskinesias associated with STN-DBS. We propose that pallidofugal fiber tracts play a major role in the etiopathology of dyskinesias and their blockade through DBS… CONTINUE READING

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