Stimulation of skin sympathetic nerve discharge by central command. Differential control of sympathetic outflow to skin and skeletal muscle during static exercise.

@article{Vissing1991StimulationOS,
  title={Stimulation of skin sympathetic nerve discharge by central command. Differential control of sympathetic outflow to skin and skeletal muscle during static exercise.},
  author={S. Vissing and U. Scherrer and R. Victor},
  journal={Circulation research},
  year={1991},
  volume={69 1},
  pages={
          228-38
        }
}
Microneurographic measurements of muscle sympathetic nerve activity (SNA) have suggested that, during static exercise, central command is much less important than skeletal muscle afferents in causing sympathetic neural activation. The possibility remains, however, that the sympathetic discharge produced by central command is targeted mainly to tissues other than skeletal muscle. To examine this possibility, we recorded SNA with microelectrodes placed selectively in skin, as well as in muscle… Expand
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References

SHOWING 1-10 OF 45 REFERENCES
Effects of partial neuromuscular blockade on sympathetic nerve responses to static exercise in humans.
TLDR
In 11 additional subjects, the heart rate responses during curare were greatly attenuated by atropine but were not significantly affected by propranolol, and arterial pressure, heart rate, and muscle sympathetic nerve activity were measured with microelectrodes. Expand
Microneurographic studies of the mechanisms of sympathetic nerve responses to static exercise in humans.
TLDR
Data indicate that muscle sympathetic nerve activity is increased by stimulation of chemically sensitive muscle afferents during static exercise in humans. Expand
General characteristics of sympathetic activity in human skin nerves.
TLDR
The sympathetic activity was not pulse synchronous as in muscle nerves and the spontaneous sympathetic volleys occurred largely independently of spontaneous blood pressure variations, indicating a relative lack of baroreflex control of the vasoconstrictor outflow to the skin. Expand
Sympathetic outflow to resting muscles during static handgrip and postcontraction muscle ischemia.
TLDR
Simultaneous microneurographic recordings of muscle sympathetic activity in the radial and the peroneal nerves of seven healthy subjects show that stimulation of chemosensitive endings in forearm muscles induces differentiation of sympathetic neural outflow to muscles in the leg and the contralateral arm. Expand
Stimulation of Renal Sympathetic Activity by Static Contraction: Evidence for Mechanoreceptor‐Induced ReflexesFrom Skeletal Muscle
TLDR
It is concluded that, in anesthetized animal preparations, mechanoreceptors with group III afferents contribute to the reflex stimulation of renal sympathetic outflow evoked by muscular contraction. Expand
Manoeuvres affecting sympathetic outflow in human skin nerves.
TLDR
It was concluded that most manoeuvres had different effects in the two nerve types, thereby confirming earlier indirect evidence for selective regional control of the sympathetic outflow. Expand
Sympathetic nerve discharge is coupled to muscle cell pH during exercise in humans.
TLDR
The principal new conclusion is that activation of muscle sympathetic outflow during exercise in humans is coupled to the cellular accumulation of protons in contracting muscle. Expand
Effects of static muscular contraction on impulse activity of groups III and IV afferents in cats.
TLDR
The results suggest that although both groups III and IV muscle afferents contribute to the reflex cardiovascular increases evoked by static exercise, group III fibers were likely to be stimulated by the mechanical effects of muscular contraction, whereas at least some group IV fibers werelikely to be stimulating by the metabolic products of muscular contractions. Expand
Discharge patterns of sympathetic neurons supplying skeletal muscle and skin in man and cat.
TLDR
Comparisons of discharge patterns of spontaneous activity in postganglionic neurons with resting activity as well as their reflex responses to various stimuli have been compared for both species. Expand
Impairment of sympathetic activation during static exercise in patients with muscle phosphorylase deficiency (McArdle's disease).
TLDR
The principal new conclusion is that defective glycogen degradation in human skeletal muscle is associated with a specific reflex impairment in sympathetic activation during static exercise. Expand
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